Research Princess Máxima Center on childhood cancer and genetic predisposition
Physician-researchers Jette Bakhuizen and Sebastian Bon are conducting research to improve diagnostics for genetic predisposition to childhood cancer. The results of these studies have led to changes in genetic testing policies. A video has also been made for children and parents explaining what genetic testing is and what the advantages and disadvantages are.
In DNA testing, we look at a child’s genetic material to see what changes have contributed to the development of cancer cells,’ explains Jette Bakhuizen. ‘We look at both tumor cells and healthy cells that reflect the child’s genetic predisposition. This helps not only to make an accurate diagnosis, but also to determine the best treatment.’
‘It is important to understand that DNA testing of normal cells can not only help the child with cancer, but also be of value to family members. If we find a hereditary predisposition, relatives can be monitored, which can help with early detection of cancer. This opens up possibilities for better treatments,’ says Sebastian Bon.
Jette Bakhuizen: ‘At diagnosis, only a limited number of cancer predisposition genes will be tested, only those that can really help in diagnosis and in choosing the right treatment. If the pediatric oncologist or parents have questions about genetic predisposition, a child can still be referred to the clinical geneticist. Because we believe it is important to investigate new forms of genetic predisposition in cancer with cancer, we will ask all children and parents for their permission to participate in scientific research about genetic predisposition.’
In the interactive video on genetic predisposition, Sebastian Bon explains genetic testing step by step. When is genetic testing done? What are the (dis)advantages? What are the possible consequences?
Utrecht Science Week: René van Westen on a colder Netherlands in a warmer world
The Earth is warming, yet the Netherlands could face much colder winters in the future. It may sound contradictory, but the explanation lies in the Atlantic Meridional Overturning Circulation (AMOC), a large system of ocean currents that transports heat and salt through the Atlantic Ocean. This circulation plays an important role in the mild climate that we are accustomed to in the Netherlands.
Utrecht Science week: The Future of Veterinary Medicine Requires New Ways of Working Together
Veterinary medicine is changing rapidly. New technologies and AI are entering the field, issues surrounding animal health and welfare are becoming increasingly complex, and the labour market is under pressure. At the same time, there is a growing need for professionals who not only have up-to-date expertise, but who can continue to develop throughout their careers and collaborate across disciplines.
Interview with Michiel van der Stelt: Water dialogue during Utrecht Science Week: Dive into the Future of Our Water
Water affects everything from our health and nature to the way we design our cities and shape our economy. But how can we ensure that our water system remains resilient to climate change and other challenges in the future?
Opening Utrecht Science Week with keynote by Juliette Legler on the hidden influence of environmental chemicals
On Friday, September 25, the annual science festival ‘Utrecht Science Week’ kicks off once again at Utrecht Science Park. We are pleased to announce that this year, Prof. Dr. Ir. Juliette Legler will deliver the Utrecht Science Lecture. Juliette Legler is Professor of Toxicology at the Faculty of Veterinary Medicine at Utrecht University and leads the ‘One Health Toxicology’ group at the Institute for Risk Assessment Sciences (IRAS).